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Year Number of Results
2015 1
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2018 5
2019 1
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2023 4
2024 2

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21 results

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Page 1
Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.
Huang YH, Chen CW, Sundaramurthy V, Słabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, Huang Y, Cheng X, Meissner A, Valk PJM, Van Maldergem L, Sanders MA, Blundell JR, Li W, Ebert BL, Goodell MA. Huang YH, et al. Among authors: reyes jm. Cancer Discov. 2022 Jan;12(1):220-235. doi: 10.1158/2159-8290.CD-21-0560. Epub 2021 Aug 24. Cancer Discov. 2022. PMID: 34429321 Free PMC article.
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment.
Winter GE, Mayer A, Buckley DL, Erb MA, Roderick JE, Vittori S, Reyes JM, di Iulio J, Souza A, Ott CJ, Roberts JM, Zeid R, Scott TG, Paulk J, Lachance K, Olson CM, Dastjerdi S, Bauer S, Lin CY, Gray NS, Kelliher MA, Churchman LS, Bradner JE. Winter GE, et al. Among authors: reyes jm. Mol Cell. 2017 Jul 6;67(1):5-18.e19. doi: 10.1016/j.molcel.2017.06.004. Epub 2017 Jun 29. Mol Cell. 2017. PMID: 28673542 Free PMC article.
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Chen CW, Zhang L, Dutta R, Niroula A, Miller PG, Gibson CJ, Bick AG, Reyes JM, Lee YT, Tovy A, Gu T, Waldvogel S, Chen YH, Venters BJ, Estève PO, Pradhan S, Keogh MC, Natarajan P, Takahashi K, Sperling AS, Goodell MA. Chen CW, et al. Among authors: reyes jm. Cell Stem Cell. 2023 Nov 2;30(11):1503-1519.e8. doi: 10.1016/j.stem.2023.09.011. Epub 2023 Oct 19. Cell Stem Cell. 2023. PMID: 37863054
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Ramabadran R, Wang JH, Reyes JM, Guzman AG, Gupta S, Rosas C, Brunetti L, Gundry MC, Tovy A, Long H, Gu T, Cullen SM, Tyagi S, Rux D, Kim JJ, Kornblau SM, Kyba M, Stossi F, Rau RE, Takahashi K, Westbrook TF, Goodell MA. Ramabadran R, et al. Among authors: reyes jm. Nat Cell Biol. 2023 Apr;25(4):528-539. doi: 10.1038/s41556-023-01109-9. Epub 2023 Apr 6. Nat Cell Biol. 2023. PMID: 37024683 Free PMC article.
High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program.
Labbé DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, Ross A, Schaeffer EM, Gibb EA, Takhar M, Den RB, Lehrer J, Karnes RJ, Freedland SJ, Davicioni E, Spratt DE, Ellis L, Jaffe JD, DʼAmico AV, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, Brown M. Labbé DP, et al. Among authors: reyes jm. Nat Commun. 2019 Sep 25;10(1):4358. doi: 10.1038/s41467-019-12298-z. Nat Commun. 2019. PMID: 31554818 Free PMC article.
Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation.
Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando T, Brunet A, Parchem RJ, Rau RE, Goodell MA. Reyes JM, et al. iScience. 2024 Feb 5;27(3):109122. doi: 10.1016/j.isci.2024.109122. eCollection 2024 Mar 15. iScience. 2024. PMID: 38414863 Free PMC article.
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Chen CW, Zhang L, Dutta R, Niroula A, Miller PG, Gibson CJ, Bick AG, Reyes JM, Lee YT, Tovy A, Gu T, Waldvogel S, Chen YH, Venters BJ, Estève PO, Pradhan S, Keogh MC, Natarajan P, Takahashi K, Sperling AS, Goodell MA. Chen CW, et al. Among authors: reyes jm. Cell Stem Cell. 2024 Feb 1;31(2):275-277. doi: 10.1016/j.stem.2024.01.001. Cell Stem Cell. 2024. PMID: 38306995 Free PMC article. No abstract available.
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
Tovy A, Rosas C, Gaikwad AS, Medrano G, Zhang L, Reyes JM, Huang YH, Arakawa T, Kurtz K, Conneely SE, Guzman AG, Aguilar R, Gao A, Chen CW, Kim JJ, Carter MT, Lasa-Aranzasti A, Valenzuela I, Van Maldergem L, Brunetti L, Hicks MJ, Marcogliese AN, Goodell MA, Rau RE. Tovy A, et al. Among authors: reyes jm. Haematologica. 2022 Apr 1;107(4):887-898. doi: 10.3324/haematol.2021.278990. Haematologica. 2022. PMID: 34092059 Free PMC article.
21 results